An SKKU research team led by Professor Kye Won Park from the Department of Food Science and Biotechnology discovered that the protein PRDM4 could act as a tool to reduce obesity. Professor Park’s team observed that PRDM4, which is found in Butein (originated from poison herbs), transformed white adipose tissue into brown adipose tissue. This transformation is known to play a major role in human metabolism.
This research is vital, as it paves a new way to control the obesity issue in our current society, as metabolism is known to be one cure to obesity. PRDM4 can also be a new possible cure to metabolic diseases. Furthermore, the function of PRDM4 provides an area for the future development of the next generation of metabolism supplements.
The team further added that the current target of diet pills can be divided into appetite inhibition, absorption inhibition, and increasing metabolism. However, pills for appetite inhibition have negative effects on neural activities, and absorption inhibition pills have hygienic and societal issues. If a drug can be developed by using PRDM4, which is a natural protein, the issues with current pills could be resolved.
Professor Park’s research was published online in Nature Chemical Biology on May 9, 2016.
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